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Microelectronics to Nanobiosensing

03/02/16     The technology of shrinking or ‘micro-sizing’ things is very challenging but plays an extremely important role in todays world. Starting with microelectronics, the concept of miniaturization has been studied and applied to life sciences and biotechnology with prospective results. Molecular behavior at micro- and even nanoscale has demonstrated to be substantially different than at the bulk scale. Microfluidics and nanofluidics technology allows researchers to achieve a more profound understanding of these variations aiming to optimally exploit their benefit in a broad spectrum of application fields. Examples of this include nanobiochips that stretch DNA for DNA sequencing and disposable nanofluidic devices that are used in point-of-care diagnostics.

Micro technology is impacting an array of applications including a more specific target delivery system which allows for the use of lower doses, minimizes side effects, avoids cytotoxicity and improves therapy. In the field of cancer research, the use of magnetic targeting guides nanoparticles to a specific body region, controlling the treatment at cell-level instead of treating the entire body which results in negative side effects.


Micro molded clear needle arrays
Among the most lucrative markets for nanobiotechnologies, medical and life science applications appear first. The advent of nanobiotechniques by hand of LOC devices and nanoenabler drug delivery methods, along with a number of novel experimental medicine and clinical/preclinical studies for early clinical trials, have become micro and nanofluidic techniques as the starring technologies for next-decades developments. These nanoscale medical devices are 100-10,000 times smaller than human cells and is having a major positive impact on drug delivery systems, health monitoring and disease diagnosis/screening.

The innovation landscape in nanofluidic devices and nanobiosensors is unlimited. Nano and micro technology are making significant changes in the medical industry. We are priviledged to be a part of this amazing technology!